Molecule's structure reveals new therapeutic opportunities for rare diabetes (EurekAlert, 13 March 2013)

14 Mar 2013


A paper in Nature describes the complete three dimensional crystal structure of the hepatocyte nuclear factor four alpha, and combines this with DNA binding and transcription studies to identify structural mechanisms for the receptor's link to maturity-onset diabetes of the young type 1.

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Adrenal Diabetes Metabolism Obesity Cardiovascular Bone Endocrine-Disrupting Chemicals Endocrine-Related Cancer Neuroendocrinology Reproduction Steroid and Steroidogenesis Thyroid

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