A procedure used in preconception diagnosis can lead to problems with pregnancies (EurekAlert, 7 April 2011)

Researched published in the American Journal of Human Genetics suggests that using a part of a human egg that does not go on to become an embryo - the polar body - in genetic tests may not allow for an adequately sensitive test for mitochondrial diseases. The authors add that all polar bodies that were mutation-free were associated with eggs that were mutation-free.

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