Vitamin D and PTH during pregnancy

The relationship between serum concentrations of parathyroid hormone (PTH) and vitamin D has been studied extensively in non-pregnant adults, but to a much lesser extent during pregnancy. Haddow and colleagues measured serum PTH and 25-hydroxy vitamin D in a cross-sectional sample of pregnant women, finding that the PTH/25-hydroxy vitamin D relationship is weaker during early pregnancy than in non-pregnant adults, making it unreliable for estimating vitamin D sufficiency. A suitable reference point for sufficiency might be the maternal 25-hydroxy vitamin D level considered sufficient for adequate transfer to neonates. Haddow et al. (2011) Clinical Endocrinology 75 309-314.

Read the full article at: DOI: 10.1111/j.1365-2265.2011.04066.x.