Usefulness of dynamic MRI enhancement measures

Distinguishing between corticotropin (ACTH)-producing pituitary adenoma (Cushing disease) and occult ectopic ACTH syndrome (EAS) can be problematic.

Guo et al.  hypothesised that dynamic magnetic resonance imaging (DMRI) could prove to be useful in the differentiation of different subtypes of adenomas with different vascular characteristics and conducted a retrospective pilot study

Their study shows that enhancement parameters in DMRI can help distinguishing ACTH producing from nonfunctioning pituitary adenomas, which could be useful in the differential diagnosis between ACTH-producing pituitary adenomas and ectopic ACTH syndrome complicated with nonfunctioning pituitary adenoma.

Read full article by Guo et al. (2015) “Usefulness of dynamic MRI enhancement measures for the diagnosis of ACTH-producing pituitary adenomas” Clinical Endocrinology vol 82 pp 267-273. DOI: 10.1111/cen.12475