26 Apr 2011
Network biology is a novel way to study complex disorders, where genetics, gene expression and physiology are integrated. The project aims at studying the gene/protein networks that drive type 2 diabetes to identify disease mechanisms and targets that can be exploited for specific treatment. The project has a strong focus on the characterisation of single-cell gene networks to better understand how heterogeneity within a cell population affects disease progression and treatment response. The project is technically advanced, and we will combine molecular biology, electrophysiology and cell-physiological techniques, including imaging and optogenetics, in animal models and human pancreatic islets. In addition, the human relevance will be examined by genetic analyses of patient cohorts.
Applicants should have a PhD degree and a strong background in molecular biology and/or cell physiology, including work with transfections, DNA constructs and expression systems. Previous experience from imaging and optogenetics is an advantage but is not essential. Further information can be found by clicking on the link below. The closing date for applications is 16 May 2011.
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