19 Oct 2011
Improved understanding of the development of the pituitary gland and forebrain, and the identification of transcription factors important in this process, has led to the discovery of three genes involved in SOD. The first gene to be recognized as a cause of SOD was HESX1, a human homeobox gene that has been found to be important in mice in the development of the forebrain, eyes and pituitary gland, and at least 8 HESX1 mutations have now been linked to SOD in humans. Two other genes, SOX2 and OTX2, have recently been reported in patients with monolateral/bilateral anophtalmia or microphtalmia, combined or multiple pituitary hormone deficiencies, and forebrain abnormalities.
Click on the link below for details on how to apply for this post. The deadline for applications is 18 December 2011.
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