Research Associate: Epigenetic Control of Seasonal Hormone Rhythms, University of Manchester, UK

The University of Manchester seeks a post-doctoral researcher to investigate underlying mechanisms that control biological timing, melatonin action and pituitary hormone function. The project uses seasonal sheep, and novel genomic tools developed by collaborators at the Roslin Institute. Approaches include studies of the role of reversible methylation and cellular plasticity, chromatin immunoprecipitation studies, and investigations of the dynamic interaction with key endocrine targets and rhythmic gene expression. This exciting position builds on a long-term collaboration with Professor David Burt (Comparative Genomics Group, Roslin Institute) and Professor Alan McNeilly (MRC Human Reproductive Biology Centre at Edinburgh). The post is funded by a BBSRC grant to both Edinburgh and Manchester and is available for a 3-year period to be based in Manchester. The successful applicant will be working in joint shared laboratories of Professors Andrew Loudon and Julian Davis (co PIs). The applicant will work closely with a team at the Roslin Institute, and exploit novel cutting edge genome analytical tools.

Applicants must hold a PhD in a biological discipline, as appropriate, and have at least one publication in an international journal. Experience in molecular and/or cell biology techniques is essential, and recent experience of use of tools to investigate epigenetic mechanisms would be an asset but not essential. Further information about the laboratories can be found at www.manchester.ac.uk/research/Andrew.loudon and for the Roslin Institute at www.roslin.ed.ac.uk.

Informal enquiries can be made to Andrew Loudon: email: [email protected], telephone: 0161 2753888.

For more information on the position, please visit the job advert. The deadline for applications is 31 January 2013.