Postdoctoral Training Fellow in HPA function

14 Nov 2019


Job title: Postdoctoral Training Fellow
Location: The Francis Crick Institute, Midland Road, London
Contract: Fixed-term, 4 years
Full time
Salary: Competitive with benefits, subject to skills and experience
Vacancy ID:        012106
 
The closing date for applications is Sunday, 1st December at 23:30.
Find out more and apply at www.crick.ac.uk/careers-study
 
Role of median eminence glial cells for hypothalamo-pituitary axis functionality
 
A postdoctoral research post funded by the MRC in the laboratory of Dr. Robin Lovell-Badge is now available. We are looking for a highly motivated scientist to identify the origin of pituitary deficiencies that develop in up to 50% of paediatric cancer survivors after cranial irradiation. Recent published work, and data obtained in our lab suggest that supporting glial cells are required in the median eminence, the structure where information between the hypothalamus and pituitary is exchanged, and that their destruction by irradiation may underline development of pituitary deficiencies. The aim of this project is to assess this hypothesis in mice and characterise the role of this cell population in the hypothalamo-pituitary axis, with a particular emphasis on the establishment of neuro-vascular connections.

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