26 Apr 2011
Funding is immediately available for a post doctoral level research scientist (flexible start date). The overall objective of Switchbox is to exploit better knowledge of homeostatic mechanisms to facilitate maintenance of health from early life through to aging. Focus will be on metabolic homeostasis integrated by the hypothalamus, which via its reciprocal projections to other brain regions and the periphery, regulates both metabolic and mental health. The successful applicant will carry out rodent studies designed to identify physiological and molecular mechanisms underlying developmental programming and how they affect homeostatic elasticity during aging.
The job opportunity is within the laboratory of the project coordinator (based in central Paris, France). The team led by Prof Barbara Demeneix has recently shown that thyroid hormone exerts negative feedback on hypothalamic type 4 melanocortin receptor (Mc4R) expression, part of the leptin/energy homeostatsis signaling pathway (Decherf et al. PNAS 2010).
Click on the link below for further information; the closing date for applications is 13 June 2011.
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