PhD studentship: Mechanisms regulating cell signalling of G protein-coupled receptors and its impact on reproductive health, Imperial College London

Via www.findaphd.com. Precise control of cellular communication and signalling are crucial for normal development and fertility in humans. These physiological processes are controlled by a cascade of cellular events initiated by specific hormones, many of which are activate specific G protein-coupled receptors (GPCRs) in target tissues. The group’s objective is to understand the fundamental mechanisms regulating hormone signalling, via GPCRs. As disrupting the regulation of GPCRs in humans underlies many diseases including reproductive disorders and pregnancy complications, such as polycystic ovarian syndrome, ovarian cancer, infertility, recurrent miscarriage and pre-term births, a crucial goal is to understand the consequences of these molecular processes on both normal physiological function and in disease.

This three-year studentship is available from 4 January 2012, though an earlier start date may be possible. The studentship is funded by the Genesis Research Trust and provides fees and a stipend. The position is restricted to UK residents or EU applicants. Applicants should send a curriculum vitae and the names of two academic referees to Dr Aylin Hanyaloglu at [email protected] by 19 September 2011. Short-listed candidates will be invited to visit the department for an interview in early October.

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