Oxidative stress and thyroid cancer

Thyroid cancer is the most common endocrine cancer. High production of reactive oxygen species can result in oxidative stress which is involved in the pathophysiology of cancers, though the understanding of these systems is limited. Wang and colleagues investigated the relationship between markers of oxidative stress and serum thyroid profiles in thyroid cancer patients. They found that levels of oxidants increased and antioxidants decreased in thyroid cancer patients compared with controls. The oxidative stress index (ratio of total oxidant status to total antioxidant status), which was significantly higher in thyroid cancer patients, was the best marker for clinicians to distinguish cancer patients from those with other thyroid disease. Wang et al. (2011) Endocrine-Related Cancer 18 773–782.

Read the full article at: DOI:10.1530/ERC-11-0230.