Obesity, diabetes mellitus, and cancer

In this editorial, Wouter de Herder and Charis Eng introduce six special reviews in a focus issue of Endocrine-Related Cancer on the global problem of interlinked obesity, type 2 diabetes mellitus and cancer. The focus issue discusses the epidemiological evidence for a link between insulin resistance and cancer; the relationship between diabetes and pancreatic cancer; the role of IGF in the association of obesity, diabetes and cancer; the evidence suggesting a connection between metabolic conditions and prostate cancer risk; the clinical consequences and potential mechanisms behind mitogenesis by insulin analogues; and the cancer risks or benefits of new incretin-based antidiabetic therapy. de Herder and Eng (2012) Endocrine-Related Cancer 19 E5–E7.

Read the full article at: DOI: 10.1530/ERC-12-0264