Long-term prognosis in pediatric pheochromocytoma

A third of patients with paraganglial tumors, pheochromocytoma, and paraganglioma, carry germline mutations in one of the susceptibility genes, RET, VHL, NF1, SDHAF2, SDHA, SDHB, SDHC, SDHD, TMEM127, and MAX. Despite increasing importance, data for long-term prognosis are scarce in pediatric presentations. Using the European–American–Pheochromocytoma–Paraganglioma Registry as a platform, Bausch and colleagues report the first and only population-based study of longterm outcomes in pediatric pheochromocytoma.

Read the full article at Bausch et al. (2014) Endocrine-Related Cancer 21; 17–25; DOI: 10.1530/ERC-13-0415