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End-stage renal disease patients can display features of hypercortisolism, but are difficult to diagnose as having Cushing’s syndrome. Raff and Trivedi investigated the plasma and salivary cortisol in end-stage renal patients, finding a discernable circadian rhythm with a significantly higher nadir (at 1800-2400 hours) compared to healthy controls. Raff and Trivedi (2012) Endocrine Connections 1, 134-142.

Read the full (Open Access) article in DOI: 10.1530/EC-12-0058.

HPA axis rhythms in end-stage renal disease

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