Growth hormone regimens in Australia

The growth hormone (GH) treatment programme in Australia is different from most other programmes around the world in four main ways: the use of auxological assessment; dosing in mg/m2 rather than in mg/kg; a comparatively low 4.5 mg/m2/week GH starting dose; and a six-monthly dose increment interval. In this study, Hughes and colleagues compare the efficacy of the Australian system with other programmes. Their analysis suggests a higher starting dose in the range of 6.4–6.9 mg/m2/week for idiopathic GH-deficient patients and 8.9 mg/m2/week for idiopathic short stature patients. Hughes et al. (2012) Clinical Endocrinology 77 62–71.

Read the full article at DOI:10.1111/j.1365-2265.2011.04230.x