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McKenna and Murray analyzed 41 low-dose daily Vitamin D supplementation studies, finding that the Endocrine Society’s Clinical Practice Guideline (CPG) underestimates the Vitamin D dose response in patients at risk of Vitamin D deficiency. Finding a Vitamin D dose-response nearly fourfold higher than the CPG estimate, they suggest a supplementation rate constant of 5.0 nmol/l per 100 IU per day.

Read the full article in McKenna and Murray (2013) Endocrine Connections 2 87–95 DOI: 10.1530/EC-13-0008

Estimating Vitamin D dose

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