Early-stage researcher position: Effect of oxidative damage on hES cells signalling pathways, Cremona, Italy

Added via Euraxess. The EpiHealthNet ITN aims at investigating the genetic and epigenetic mechanisms acting during peri-conception oocyte and embryo development and their long-term effect on adult health and longevity. Both in vivo animal models of maternal diabetes and obesity and in vitro models of animal and human embryonic stem cells will be developed by 6 academic partners and 3 industrial partners across Europe.

The candidate will work on a project focused on the “Effect of oxidative damage on human embryonic stem cells signalling pathways” and more specifically he/her will investigate transcriptomic changes and molecular pathways affected by exposure to oxidative stress and their long term consequence on cell viability, pluripotency and ability to differentiate in multiple cell types, with specific reference to the vascular phenotypes. The candidate will have the possibility for collaboration, networking and will spend short periods in laboratories of other EpiHealthNet partners for training purposes. The candidate will have the additional opportunity of in-house training on embryo related technologies.

The Fellowship is open to international candidates who hold or expect to obtain a Master’s degree in Life Sciences. Eligible applicants must, at the time of recruitment by the host organisation, be in the first four years (full-time equivalent research experience) of their research careers and not yet have been awarded a doctoral degree. The candidate should have a background in cell biology, preferably developmental biology, and molecular biology, experience in cell culture is required, preferably stem cell culture, experience in RT-PCR, qPCR and knowledge in regulation of gene expression is preferred. Proficiency in english is required.

The deadline for applications is 15 August 2013. For more information please visit the job advert.