BiosciNews

The selective progesterone receptor agonist dienogest is widely used to treat endometriosis, an estrogen-dependant disease. Mori and colleagues elucidated the effect of dienogest on enzymes involved in local estrogen metabolism in endometriosis, finding that dienogest exerts comprehensive inhibition of abnormal estrogen production through inhibition of aromatase and HSD17β1.

Read the full article at Mori et al. (2015) Journal of Endocrinology 225 69–76.