08 Aug 2013
Congenital ACTH and GH deficiency can present with hypoglycaemia at birth or in young children, as cortisol and GH play key roles in glucose homeostasis. As recurrent severe hypoglycaemia negatively impacts neurocognitive development, effective replacement therapy is crucial for the neurological outcome in these patients. Cambiaso and colleagues used continuous glucose monitoring to detect nocturnal asymptomatic hypoglycaemic episodes and optimize the hydrocortisone regimen in children with congenital ACTH and GH deficiency.
Read the full article in Clinical Endocrinology 79 232–237, DOI: 10.1111/cen.12123.
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