Challenges in a patient with type 1 diabetes

Jassam et al. report on a patient with type 1 diabetes and a challenging clinical scenario where immune-mediated tissue resistance and circulatory insulin antibodies underlined the pathophysiology of this patient.

It was the first time that insulin recovery studies were used routinely as a surrogate marker of disease activity. The laboratory had a major role in this case and the use of the differential insulin assays shed light on the kinetics of insulin resistance in this patient.

In this case report, they describe the clinical course of this patient, with use of surrogate markers to monitor disease activity and treatment modalities used to maintain normoglycaemia.

Read full Case Report at DOI:10.1530/EDM-13-0086