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Fibroblasts have long been suggested to participate in tumour initiation and progression, possibly by inducing the key metastatic cellular process of epithelial-to-mesenchymal transition (EMT). Soon and colleagues demonstrate that fibroblasts cultured from within breast cancer tissue induced EMT in normal tissue, and are resistant to chemotherapy. Soon et al. (2013) Endocrine-Related Cancer 20, 1–12.

Read the full article at DOI: 10.1530/ERC-12-0227.

Breast cancer fibroblasts induce EMT

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