Levoketoconazole, which inhibits cortisol synthesis, has been approved by the US Food and Drug Administration for treating Cushing syndrome.
Research published in the Annals of Internal Medicine shows that benign adrenal tumours are much more likely to cause mild autonomous cortisol secretion (MACS) than previously recognised, and are a strong risk factor for high blood pressure and type 2 diabetes.
According to a Dutch study, published in The Journal of Clinical Endocrinology & Metabolism, there is no benefit of morning vs. evening hydrocortisone administration for 21-hydroxylase deficiency in children and adolescents.
According to a mouse study, published in Nature Communications, stress hormones are able to reduce our immune protection from harmful gut bacteria and can lead to inflammatory flare ups, such as Crohn’s disease.
A study published in The Journal of Clinical Endocrinology & Metabolism indicates that children may not need additional growth-promoting therapies if their congenital adrenal hyperplasia is well managed.
Elevated levels of stress hormones predispose people with normal blood pressure to develop high blood pressure and cardiovascular disease, according to a study published in Hypertension.